BDBM255545 US9499523, 19

SMILES Nc1cnc(cn1)-n1c(nc2c(Cl)ccc(Cl)c2c1=O)[C@@H](Nc1ncnc(N)c1Cl)C1CC1

InChI Key InChIKey=AKQFGWZLEYAUFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 255545   

LigandPNGBDBM255545(US9499523, 19)
Affinity DataIC50: 360nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent

LigandPNGBDBM255545(US9499523, 19)
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent

LigandPNGBDBM255545(US9499523, 19)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent