BDBM255528 US9499523, 2

SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cnc(N)cn1

InChI Key InChIKey=AEIAUSDERBJKPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 255528   

LigandPNGBDBM255528(US9499523, 2)
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
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LigandPNGBDBM255528(US9499523, 2)
Affinity DataIC50: 3.5nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent

LigandPNGBDBM255528(US9499523, 2)
Affinity DataIC50: 630nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent