BDBM254932 US9499542, 15::US9675594, 15

SMILES Cc1cc(ccc1CN1CCOCC1)-c1cc(Nc2ccn(C)n2)nc2[nH]cc(C#N)c12

InChI Key InChIKey=ANIYDVYTJUHGSI-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 254932   

LigandPNGBDBM254932(US9675594, 15 | US9499542, 15)
Affinity DataIC50: 1nMpH: 8.5 T: 2°CAssay Description:LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM254932(US9675594, 15 | US9499542, 15)
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM254932(US9675594, 15 | US9499542, 15)
Affinity DataEC50:  1nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM254932(US9675594, 15 | US9499542, 15)
Affinity DataEC50:  4nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...More data for this Ligand-Target Pair
In DepthDetails
US Patent