BDBM254096 US9493474, 8B

SMILES Cc1c2COC(=O)c2ccc1[C@H](O)CN1CCC2CN(CC12)S(=O)(=O)c1ccc(cc1)C#N

InChI Key InChIKey=IHYVNCXXQXINLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254096   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM254096(US9493474, 8B)
Affinity DataIC50: 662nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent