BDBM252950 US9464076, 102::US9464076, 103::US9464076, 104::US9464076, 105::US9464076, 106::US9464076, 107::US9464076, 121::US9464076, 122::US9464076, 123

SMILES COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(cccc4n3)C(=O)N3CC(C3)OC)c(C)c12

InChI Key InChIKey=KHOQORNSGLHMHG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 252950   

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.700nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 2.10nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.730nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.570nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.290nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252950(US9464076, 102 | US9464076, 122 | US9464076, 121 |...)
Affinity DataIC50: 0.220nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent