BDBM252887 US9464076, 116::US9464076, 39::US9464076, 40::US9464076, 41

SMILES COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CC[C@@H](O)C4)c4ccccc4n3)c(C)c12

InChI Key InChIKey=UXOLHRWLSKHKNL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 252887   

LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.650nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.350nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent

LigandPNGBDBM252887(US9464076, 39 | US9464076, 40 | US9464076, 41 | US...)
Affinity DataIC50: 0.150nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
Go to US Patent