BDBM251924 US10065961, Compound 26::US9475814, 26

SMILES C[C@H]1N(CCn2c1nnc2-c1nc(C)co1)C(=O)c1ccc(cc1)-c1cccs1

InChI Key InChIKey=WDEZNVHYSZEMLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251924   

TargetNeuromedin-K receptor(Human)
Euroscreen

US Patent
LigandPNGBDBM251924(US9475814, 26 | US10065961, Compound 26)
Affinity DataIC50: 12nMAssay Description:Changes in intracellular calcium levels are a recognized indicator of G protein-coupled receptor activity. The efficacy of compounds of the invention...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
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TargetNeuromedin-K receptor(Human)
Euroscreen

US Patent
LigandPNGBDBM251924(US9475814, 26 | US10065961, Compound 26)
Affinity DataIC50: 12nMAssay Description:The antagonist activity of compounds of the invention is measured following pre-incubation (3 minutes) of the compound with the cells, followed by ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent