BDBM251876 US9475806, 9-D b) (-)

SMILES CNC(c1nc2cc(cnc2[nH]1)C#N)(c1c(OC)cc(C)c2[nH]ccc12)C(F)(F)F

InChI Key InChIKey=QKNPPIQDEBBNJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251876   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM251876(US9475806, 9-D b) (-))
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent