BDBM251494 US9452998, 43

SMILES NC1CCN(CC1F)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1OC(F)(F)F

InChI Key InChIKey=SUKUYCBPKLCSMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251494   

TargetProtein kinase C alpha type(Human)
Novartis

US Patent
LigandPNGBDBM251494(US9452998, 43)
Affinity DataIC50: 0.300nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent

TargetProtein kinase C theta type(Human)
Novartis

US Patent
LigandPNGBDBM251494(US9452998, 43)
Affinity DataIC50: 2.20nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent