BDBM250480 US9464044, 113

SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc([N-]S(=O)(=O)c4cccc(Cl)c4F)c1)C(C3)C2

InChI Key InChIKey=ITBUKDRUGQRJPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250480   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250480(US9464044, 113)
Affinity DataIC50: 2.70nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails
US Patent