BDBM24965 organophosphorus derivative, 6::{[(2S)-2-amino-3-(benzyloxy)propanamido]methyl}(methyl)phosphinic acid

SMILES CP(O)(=O)CNC(=O)[C@@H](N)COCc1ccccc1

InChI Key InChIKey=AEPNQCQDJBIFMP-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24965   

TargetUrease subunit alpha/beta/gamma(Bacillus pasteurii)
Wroclaw University of Technology

LigandPNGBDBM24965({[(2S)-2-amino-3-(benzyloxy)propanamido]methyl}(me...)
Affinity DataKi:  2.50E+4nM ΔG°:  -6.38kcal/mole IC50: 8.00E+4nMpH: 7.0 T: 2°CAssay Description:Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetUrease subunit alpha [F36L]/beta/gamma(Proteus vulgaris)
Wroclaw University of Technology

LigandPNGBDBM24965({[(2S)-2-amino-3-(benzyloxy)propanamido]methyl}(me...)
Affinity DataKi:  3.26E+4nM ΔG°:  -6.22kcal/mole IC50: 1.83E+5nMpH: 7.0 T: 2°CAssay Description:Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed