BDBM24911 3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3-ylamino)-1,2-thiazole-4-carboxamide::isothiazole, 14a

SMILES CC(Sc1nsc(Nc2cccnc2)c1C(N)=O)c1ccc(Cl)cc1

InChI Key InChIKey=BGDAUMNRCAPWMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24911   

LigandPNGBDBM24911(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed