BDBM24867 1-(2-aminophenyl)-3-[({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)amino]propan-1-one::CHEMBL252456::Pyridopyrimidine, 12l
SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CNCCC(=O)c2ccccc2N)cc1
InChI Key InChIKey=LQOQPLJMWKFALQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 24867
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of Akt2 phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of Akt1 phosphorylation in human by C33a cells by IPKA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Akt1 phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of Akt2 phosphorylation in human by C33a cells by IPKA assayMore data for this Ligand-Target Pair