BDBM24783 4H-chromen-4-one::chromone, 12

SMILES O=c1ccoc2ccccc12

InChI Key InChIKey=OTAFHZMPRISVEM-UHFFFAOYSA-N

Data  4 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 24783   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of kynuramine to 4-hydroxyquinoline conversion after 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of recombinant human MAO-A assessed as inhibition of kynuramine to 4-hydroxyquinoline conversion after 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed