BDBM24718 2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole::pyrazole-indole, 20

SMILES Cc1cc(n[nH]1)-c1cc2ccccc2[nH]1

InChI Key InChIKey=YLKJJERCKRGNPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24718   

TargetAurora kinase A(Human)
Genentech

LigandPNGBDBM24718(2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandPNGBDBM24718(2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...)
Affinity DataIC50: 510nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed