BDBM24715 5-cyclopropyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{10,15}]hexadeca-1(9),2,5,10,12,14-hexaene::Tetrahydropyrazolo[3,4-a]carbazole, 24

SMILES C1CC1c1[nH]nc-2c1CCc1c-2[nH]c2ccccc12

InChI Key InChIKey=UFESQQQWTVKFRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24715   

TargetAurora kinase A(Human)
Genentech

LigandPNGBDBM24715(5-cyclopropyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed