BDBM245983 US9433622, DMX- 80

SMILES F[C@H]1CCN(Cc2ccc(Nc3nccc(n3)-c3cnc(N4CC[C@H](F)C4)c(c3)C#N)cn2)C1

InChI Key InChIKey=ADHUWZBZAZXCOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245983   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM245983(US9433622, DMX- 80)
Affinity DataIC50: 15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM245983(US9433622, DMX- 80)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
In DepthDetails
US Patent