BDBM245958 US9433622, DMX- 30

SMILES F[C@H]1CCN(C1)c1ncc(cc1C#N)-c1ccnc(Nc2ccc(CN3CCOCC3)cc2)n1

InChI Key InChIKey=AWVBPIKRRBIMPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245958   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM245958(US9433622, DMX- 30)
Affinity DataIC50: 15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM245958(US9433622, DMX- 30)
Affinity DataIC50: 15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
In DepthDetails
US Patent