BDBM24569 (1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}dodecyl N-formylglycinate::(2S)-1-[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]tridecan-2-yl 2-formamidoacetate::Orlistat derivative, 15f::Orlistat derivative, 17a

SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CC)OC(=O)CNC=O

InChI Key InChIKey=QUCZRYAJOAFMJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24569   

TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandPNGBDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandPNGBDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed