BDBM244224 US9428501, 19

SMILES COc1ccc(CN2CCC(CC2)c2ccc3n(C)c(nc3c2)C(=O)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cn1

InChI Key InChIKey=KZBWOIGKOYKULA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244224   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Astellas Pharma

US Patent
LigandPNGBDBM244224(US9428501, 19)
Affinity DataEC50:  10nMT: 2°CAssay Description:In order to make MDA-MB-453 cell become 15000 cells per well, each 36 μl was seeded in Leibovitz's L-15 medium including 10% fetal bovine serum (m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM244224(US9428501, 19)
Affinity DataIC50: 8.5nMAssay Description:In order to make human PIK3 CA mutation-positive breast cancer cell line MDA-MB-453 cells become 500 cells per well in a 384 well non-adhesive plate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent