BDBM243458 US9427440, 5

SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3CC(=Cc2c1)C(=O)NCCN1CCN(CC1)S(=O)(=O)NC5=O

InChI Key InChIKey=HZBZHBNFMGUGEK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243458   

TargetGenome polyprotein [1027-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243458(US9427440, 5)
Affinity DataEC50:  920nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243458(US9427440, 5)
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
In DepthDetails
US Patent