BDBM243353 6-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-oxazol-2-yl}-6,9- diaza-spiro[4.5]decan- 10-one::US10053455, 009

SMILES Cc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CCCC2)n1

InChI Key InChIKey=WANSKCOCWJIGLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243353   

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243353(6-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent