BDBM243350 4-{5-[3-(4-Methyl- pyrimidin-2-ylamino)-5- morpholin-4-ylmethyl- phenyl]-oxazol-2-yl}-4,7- diaza-spiro[2.5]octan-8- one::US10053455, 006

SMILES Cc1ccnc(Nc2cc(CN3CCOCC3)cc(c2)-c2cnc(o2)N2CCNC(=O)C22CC2)n1

InChI Key InChIKey=YHZYKKLEUYUFCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243350   

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243350(4-{5-[3-(4-Methyl- pyrimidin-2-ylamino)-5- morphol...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
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US Patent