BDBM243346 2-{3-[2-(8-Oxo-4,7- diaza-spiro[2.5]oct-4-yl)- oxazol-5-yl]- phenylamino}- pyrimidine-4-carbonitrile::US10053455, 002

SMILES O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccc(n3)[N+]#[C-])c2)C11CC1

InChI Key InChIKey=STGNCRRWAKHSID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243346   

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243346(2-{3-[2-(8-Oxo-4,7- diaza-spiro[2.5]oct-4-yl)- oxa...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
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US Patent