BDBM24231 2-[4-(piperidin-1-ylmethyl)phenoxy]-1,3-benzothiazole::Benzthiazole compound, 33b

SMILES C(N1CCCCC1)c1ccc(Oc2nc3ccccc3s2)cc1

InChI Key InChIKey=JNKRNJIZLGLIJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24231   

TargetLeukotriene A-4 hydrolase(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24231(2-[4-(piperidin-1-ylmethyl)phenoxy]-1,3-benzothiaz...)
Affinity DataIC50: 59nMT: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24231(2-[4-(piperidin-1-ylmethyl)phenoxy]-1,3-benzothiaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed