BDBM24228 3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)-1,3-oxazolidin-2-one::Benzthiazole compound, 27l

SMILES O=C1OCCN1C1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1

InChI Key InChIKey=RUPCCWFCAYKMFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24228   

TargetLeukotriene A-4 hydrolase(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24228(3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...)
Affinity DataIC50: 29nMT: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24228(3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...)
Affinity DataIC50: 500nMAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed