BDBM24227 1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)pyrrolidin-2-one::Benzthiazole compound, 27j

SMILES O=C1CCCN1C1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1

InChI Key InChIKey=GIYCUMSDCASBAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24227   

TargetLeukotriene A-4 hydrolase(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24227(1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...)
Affinity DataIC50: 13nMT: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24227(1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed