BDBM24223 2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzothiazole::Benzthiazole compound, 27b

SMILES C(Cc1ccc(Oc2nc3ccccc3s2)cc1)N1CCCCC1

InChI Key InChIKey=DHHMVJVCMLXZBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24223   

TargetLeukotriene A-4 hydrolase(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24223(2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzoth...)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24223(2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzoth...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed