BDBM242027 US9415055, 2,3-dichloro-N-[2-(6-chloro-3-pyridyl)-2-morpholino-ethyl]benzamide::US9593105, 28

SMILES Clc1ccc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCOCC1

InChI Key InChIKey=BOCDCRVUZFPXEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 242027   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM242027(US9415055, 2,3-dichloro-N-[2-(6-chloro-3-pyridyl)-...)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM242027(US9415055, 2,3-dichloro-N-[2-(6-chloro-3-pyridyl)-...)
Affinity DataIC50: 3.90nMAssay Description:Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent