BDBM241866 US9416154, 8

SMILES CCCCOC(=O)[C@H](C)NP(=O)(O[C@H](CC)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(O)[C@@H]1O)Oc1cccc2ccccc12

InChI Key InChIKey=WBEIXGVCBAGXRZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241866   

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM241866(US9416154, 8)
Affinity DataEC50:  1.30E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent