BDBM240804 N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-(4-methylpiperazin-1-yl)acetamide (3e)

SMILES CN1CCN(CC(=O)Nc2ccc3nc([nH]c(=O)c3c2)-c2cc3ccccc3[nH]2)CC1

InChI Key InChIKey=TVJGFARBEBAXQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240804   

TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

LigandPNGBDBM240804(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 1.00E+4nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Sun Yat-Sen University

LigandPNGBDBM240804(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 1.00E+4nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed