BDBM240803 N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-morpholinoacetamide (3d)

SMILES O=C(CN1CCOCC1)Nc1ccc2nc([nH]c(=O)c2c1)-c1cc2ccccc2[nH]1

InChI Key InChIKey=MTSRLRFJSSBTGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240803   

TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

LigandPNGBDBM240803(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 2.02E+3nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Sun Yat-Sen University

LigandPNGBDBM240803(N-(2-(1H-indol-2-yl)-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataIC50: 3.22E+4nMpH: 8.0Assay Description:All the assays were under 0.1 M KH2PO4/K2HPO4 buffer, pH 8.0, using a Shimadzu 2450 Spectrophotometer. Enzyme solutions were prepared to give 2 units...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed