BDBM240715 US9422243, 13

SMILES Cc1cc(ccc1Cl)-c1[nH]c(=O)c2cc(F)ccc2c1OCCN

InChI Key InChIKey=KYPCNLJQBLPDKY-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 240715   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240715(US9422243, 13)
Affinity DataKd: <10nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240715(US9422243, 13)
Affinity DataKd:  34nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240715(US9422243, 13)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...More data for this Ligand-Target Pair
In DepthDetails
US Patent