BDBM240682 US9416127, 19

SMILES COc1ccc(cc1)-n1cc(nn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1

InChI Key InChIKey=AUNQKHKALVSFFC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240682   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240682(US9416127, 19)
Affinity DataKi:  1.60nM ΔG°:  -12.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240682(US9416127, 19)
Affinity DataKi:  38.8nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 ° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent