BDBM240665 US9416127, 2

SMILES Cc1nn(nc1C(=O)Nc1ccc(cc1)[C@H]1CNCCO1)-c1ccccc1

InChI Key InChIKey=KMEFEDMLPJOXGG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240665   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240665(US9416127, 2)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 ° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240665(US9416127, 2)
Affinity DataKi:  1.5nM ΔG°:  -12.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent