BDBM240117 US9403813, 21

SMILES Cc1cc(C(=O)N2CC[C@H]2c2nc(no2)-c2cccc(F)c2C)c(cc1C)-n1nccn1

InChI Key InChIKey=YJLVUGVRJGAYCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240117   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM240117(US9403813, 21)
Affinity DataIC50: 173nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM240117(US9403813, 21)
Affinity DataIC50: 4nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent