BDBM238978 US9403833, 13

SMILES Cc1c(NC(=O)c2nnn(c2C)-c2ccc(Cl)cc2C2CC2)c(=O)n(-c2ccccc2F)n1C

InChI Key InChIKey=RZYISIGSIXJKBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238978   

TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Human)
Novartis

US Patent
LigandPNGBDBM238978(US9403833, 13)
Affinity DataIC50: 3.30E+3nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent