BDBM238330 US9394273, 19::US9394273, 20

SMILES OC(Cc1ccc(F)cc1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O

InChI Key InChIKey=TZVFTSQQDVXJEF-UHFFFAOYSA-N

Data  4 KI  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 238330   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  11nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  38nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  0.200nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP3 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  952nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  5.60E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataKi:  3nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataKi:  745nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataKi:  902nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataKi:  9.29E+3nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In DepthDetails
US Patent