BDBM238314 US9394273, 3::US9394273, 4

SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O

InChI Key InChIKey=XHFNHGXDNFRXKW-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 238314   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataEC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataEC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataEC50:  1.28E+3nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataEC50:  186nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataKi:  603nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataKi:  2.31E+3nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataKi: >1.00E+4nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238314(US9394273, 4 | US9394273, 3)
Affinity DataKi: >1.00E+4nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent