BDBM238219 US9403774, 4

SMILES CNC(=O)c1ccc(cc1)-c1cccc2C(N(CCc12)C(=O)[C@H]1CC[C@H](CN)CC1)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=UZMRFTDNFYNDKS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238219   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM238219(US9403774, 4)
Affinity DataKi: <5nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent