BDBM23812 CHEMBL232728::S-Trityl-L-Cysteine (STLC) Analogue, 41::methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate

SMILES COC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DXUZZMIANHJYIU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23812   

TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM23812(methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]p...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM23812(methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]p...)
Affinity DataKi:  120nM ΔG°:  -9.43kcal/moleT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed