BDBM237569 US9394263, 1o

SMILES COc1ccc2cc(Br)ccc2c1CN1c2ccccc2OC2(CCOCC2)[C@H](NC(=O)[C@@H](N)[C@H](C)O)C1=O

InChI Key InChIKey=BVCJBHZLEXKSFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237569   

TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237569(US9394263, 1o)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237569(US9394263, 1o)
Affinity DataIC50: 5.48E+4nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent