BDBM237428 US9393232, 2.2::US9393232, 2.2a::US9393232, 2.2b

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(c2c1)c1ccccc1

InChI Key InChIKey=HIZNONHBBUUYFX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 237428   

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 55nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [1-435](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 35nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 150nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 3.60E+3nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain testis-specific protein [1-397](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 95nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent