BDBM23723 4-bromo-1-[(4-methoxyphenyl)carbonyl]-3,5-dimethyl-1H-pyrazole::N-Benzoylpyrazole deriv., 31::cid_714833

SMILES COc1ccc(cc1)C(=O)n1nc(C)c(Br)c1C

InChI Key InChIKey=NLSJGZBQMCEPIO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 23723   

TargetChymotrypsin-C(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataIC50: 7.60E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin D(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataIC50: 2.84E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetNeutrophil elastase(Human)
Montana State University

LigandPNGBDBM23723(cid_714833 | 4-bromo-1-[(4-methoxyphenyl)carbonyl]...)
Affinity DataKi:  2.45E+4nM ΔG°:  -6.29kcal/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed