BDBM237214 1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-phenylurea (6a)

SMILES COc1cc(CN(C(=O)Nc2ccccc2)c2ccc(Br)cc2)ccc1O

InChI Key InChIKey=SWULKKLLIJGMRA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237214   

TargetMitogen-activated protein kinase 1/3(Human)
Nanjing University

LigandPNGBDBM237214(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50: 2.14E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
LigandPNGBDBM237214(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1/3(Human)
Nanjing University

LigandPNGBDBM237214(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Nanjing University

LigandPNGBDBM237214(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50: 1.38E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetETS domain-containing protein Elk-1(Human)
Nanjing University

LigandPNGBDBM237214(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50: 1.24E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed