BDBM23702 3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole::N-Benzoylpyrazole deriv., 4

SMILES Cc1ccc(C(=O)c2ccn(n2)C(=O)c2ccc(F)cc2)c(C)c1

InChI Key InChIKey=XNRMQSNQFCESPA-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 23702   

TargetChymotrypsin-C(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 1.10E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAminopeptidase N(Pig)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin D(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandPNGBDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataKi:  24nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed