BDBM236811 US9388149, 9 (Diastereoisomer 1)::US9388149, 9 (Diastereoisomer 2)

SMILES COC(=O)CNCC(=O)c1cccc(Nc2c(NC(C3CCCS3)c3ccc(C)o3)c(=O)c2=O)c1O

InChI Key InChIKey=SGLBQNTUAMMYTP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 236811   

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236811(US9388149, 9 (Diastereoisomer 2) | US9388149, 9 (D...)
Affinity DataIC50: 89nMT: 2°CAssay Description: PathHunter HEK293-CXCR2 or U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well format) in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236811(US9388149, 9 (Diastereoisomer 2) | US9388149, 9 (D...)
Affinity DataIC50: 580nMT: 2°CAssay Description: PathHunter HEK293-CXCR2 or U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well format) in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236811(US9388149, 9 (Diastereoisomer 2) | US9388149, 9 (D...)
Affinity DataIC50: 80nMT: 2°CAssay Description: PathHunter HEK293-CXCR2 or U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well format) in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM236811(US9388149, 9 (Diastereoisomer 2) | US9388149, 9 (D...)
Affinity DataIC50: 153nMT: 2°CAssay Description: PathHunter HEK293-CXCR2 or U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well format) in...More data for this Ligand-Target Pair
In DepthDetails
US Patent