BDBM236354 US9365576, 107
SMILES CNC(=O)N1CCC(CC1)N1C(c2c(cc(-c3cnc(OC)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1
InChI Key InChIKey=FSAYSWYPULVFEH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 236354
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 3nMT: 2°CAssay Description:Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+3nMT: 2°CAssay Description:Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 2.69nMT: 2°CAssay Description:Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair