BDBM236352 US9365576, 105
SMILES COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)C2CCOCC2)c(OC)n1
InChI Key InChIKey=TVCFLHMUHMTBGT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 236352
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 10.2nMT: 2°CAssay Description:Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 6.29E+3nMT: 2°CAssay Description:Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 14.3nMT: 2°CAssay Description:Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair