BDBM236114 US9365563, Z1::US9878991, Compound Z1

SMILES OC[C@@H](O)c1cnc(C2=CCN(CC2)C(=O)Nc2ccc(cc2)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=UQXMGVCFIOZTBP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 236114   

LigandPNGBDBM236114(US9365563, Z1 | US9878991, Compound Z1)
Affinity DataIC50: 75.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM236114(US9365563, Z1 | US9878991, Compound Z1)
Affinity DataIC50: 11.6nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM236114(US9365563, Z1 | US9878991, Compound Z1)
Affinity DataIC50: 75.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

LigandPNGBDBM236114(US9365563, Z1 | US9878991, Compound Z1)
Affinity DataIC50: 11.6nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

LigandPNGBDBM236114(US9365563, Z1 | US9878991, Compound Z1)
Affinity DataIC50: 34nMAssay Description:Agonist activity at human TRPV1 overexpressed in HEK293 cells incubated for 1 hr by Fluo-4 AM dye based microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed